Prostamax
Prostamax (Khavinson-School Synthetic Tetrapeptide, Lys-Glu-Asp-Pro)
Mechanism of Action
Synthetic tetrapeptide (Lys-Glu-Asp-Pro) from the Khavinson bioregulator family. Published work reports deheterochromatinization (decondensation of densely packed chromatin) in lymphocytes from elderly human subjects, proposed to release age-repressed genes, plus a stimulating effect on prostatic gland explants in organotypic rat tissue culture. The peptide-DNA interaction model is described in review literature but hasn't been independently validated at the receptor level — no well-characterized receptor and no human pharmacology data exist for how a free tetrapeptide reaches and acts on target cells.
Key Benefits
- Chromatin decondensation / deheterochromatinization observed in aging human lymphocytes (ex vivo)
- Stimulating effect on prostatic gland explants in young and aged rat organotypic tissue culture
- Consistent findings across multiple Khavinson-group publications spanning two decades
- No independent validation of the proposed prostate-specific clinical benefit in humans
Dosing Protocol
Real literature exists here — six Khavinson-group papers spanning 2004–2017, including a rat prostatic-tissue study — which is a meaningfully different evidence picture than a compound with zero independent citations. But every cited study is ex vivo, in vitro, or animal tissue culture; none is a human prostate-health clinical trial. Present this compound on its actual evidence (epigenetic/chromatin research, prostate tissue-culture stimulation), not on unverified prostatitis/BPH treatment claims repeated across vendor sites.
Ideal Candidates
Research contexts modeling chromatin/epigenetic aging or the Khavinson bioregulator peptide class specifically. Not supported by any human clinical trial for prostate health — the existing literature is ex vivo/tissue-culture, not a treatment study.
Side Effects & Safety
No human clinical safety data exists in the cited literature.
Regulatory Status
Gray AreaNot on the 503A bulks list. Gray zone — sold as a supplement in Russia. Part of the Khavinson-school bioregulator peptide family, the same research tradition as Epitalon and Thymalin already in this library.
Evidence & Citations
How we source and weigh evidence- Dzhokhadze TA, et al. Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro). Georgian Med News. 2012;(212):76-82.
- Zakutskiy AN, et al. The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats. Adv Gerontol. 2006;19:93-6.
- Khavinson VKh, Lezhava TA, Malinin VV. Effects of short peptides on lymphocyte chromatin in senile subjects. Bull Exp Biol Med. 2004;137(1):78-81.
Frequently asked
What is Prostamax?+
Prostamax (Prostamax (Khavinson-School Synthetic Tetrapeptide, Lys-Glu-Asp-Pro)) is a peptide studied for khavinson bioregulator and chromatin/epigenetic research. Synthetic tetrapeptide (Lys-Glu-Asp-Pro) from the Khavinson bioregulator family. Published work reports deheterochromatinization (decondensation of densely packed chromatin) in lymphocytes from elderly human subjects, proposed to release age-repressed genes, plus a stimulating effect on prostatic gland explants in organotypic rat tissue culture. The peptide-DNA interaction model is described in review literature but hasn't been independently validated at the receptor level — no well-characterized receptor and no human pharmacology data exist for how a free tetrapeptide reaches and acts on target cells.
What is the dosing protocol for Prostamax?+
Literature commonly references No dosing established in the peer-reviewed literature (low) to No dosing established in the peer-reviewed literature; Russian OTC product labeling describes a short injectable course, not independently verified here (maintenance) via SubQ / IM (per Russian product labeling; not derived from the cited research itself), on a no clinically established human protocol cycle. Educational reference only — a licensed Stackhaus Health provider sets any personalized protocol.
What is the regulatory status of Prostamax?+
Not on the 503A bulks list. Gray zone — sold as a supplement in Russia. Part of the Khavinson-school bioregulator peptide family, the same research tradition as Epitalon and Thymalin already in this library.
Where can I access Prostamax?+
Research-grade Prostamax is available through Stackhaus Research. For a personalized, provider-reviewed protocol, consult a licensed clinician through Stackhaus Health.