Every peptide, explained
45 compounds, each mapped with mechanisms, dosing protocols, benefits, side effects, and regulatory status. Educational reference, with a provider-review path for anything personalized.
The complete peptide library
45 compoundsRetatrutide
Triple GIP/GLP-1/Glucagon Receptor Agonist (LY3437943)
A triple agonist of the GIP, GLP-1, and glucagon receptors developed by Eli Lilly, showing the strongest weight-loss data of any incretin-class compound to date — up to ~24% body weight reduction at 48 weeks in phase 2 trials.
Tesamorelin
Egrifta (FDA-approved brand)
An FDA-approved GHRH analog that specifically targets visceral abdominal fat. Reduces VAT, improves lipid profiles, and has cognition data in older adults.
NAD+
Nicotinamide Adenine Dinucleotide
The cell's central redox coenzyme, required for mitochondrial ATP production, sirtuin activity, and DNA repair. NAD+ levels decline substantially with age; direct IV/SubQ NAD+ and oral precursors (NMN, NR) are both used to raise blood NAD+ levels, with a growing but still early human clinical trial base.
MOTS-c
Mitochondrial Open Reading Frame of the 12S rRNA Type-c
A mitochondrial-derived peptide encoded within the 12S rRNA mitochondrial gene that activates AMPK to mimic key metabolic effects of exercise — improving insulin sensitivity, mitochondrial bioenergetics, and skeletal muscle function.
GHK-Cu
Copper Peptide GHK-Cu
A naturally occurring copper-binding peptide with powerful regenerative properties. Stimulates collagen synthesis, wound healing, and has potent antioxidant effects.
BPC-157
Body Protection Compound 157
One of the most versatile healing peptides. Accelerates recovery of gut lining, tendons, ligaments, and muscle tissue. Widely studied for injury repair and gut health.
Semax
ACTH 4-10 analog
A synthetic ACTH analog that upregulates BDNF, NGF, and VEGF. Enhances dopaminergic neurotransmission for improved focus, memory, and neuroprotection.
SS-31
Elamipretide / Szeto-Schiller peptide
A mitochondria-targeted antioxidant peptide that concentrates in the inner mitochondrial membrane, reduces oxidative stress, and protects cardiac and renal tissue.
Epitalon
Epithalamin / Epithalon
A pineal-derived tetrapeptide that activates telomerase to elongate telomeres. Regulates melatonin production and circadian rhythms for comprehensive anti-aging.
Glutathione
GSH / Reduced Glutathione
The body's master endogenous antioxidant. Neutralizes reactive oxygen species, supports liver detoxification, and maintains immune cell function. Popular as IV infusion therapy.
TB-500
Thymosin Beta-4 fragment
A naturally occurring peptide that promotes cell migration, angiogenesis, and tissue repair. Studied for systemic healing and reducing inflammation throughout the body.
AOD-9604
Anti-Obesity Drug 9604
A fragment of HGH (amino acids 176–191) that activates beta-3 adrenergic receptors to stimulate targeted fat mobilization without the IGF-1 side effects of full HGH.
KPV
Lys-Pro-Val (MSH fragment)
A C-terminal tripeptide of alpha-MSH that binds melanocortin receptors to exert potent anti-inflammatory effects. A standard for gut inflammation and IBD research.
ARA-290
Cibinetide
An 11-amino-acid peptide engineered from the structural helix of erythropoietin that retains EPO's tissue-protective signaling without stimulating red blood cell production. Studied in randomized trials for small-fiber neuropathy, neuropathic pain, and tissue repair.
Ipamorelin
Ipamorelin acetate
A selective GH secretagogue with minimal side effects. Produces clean GH pulses without cortisol or prolactin elevation. Ideal for sleep quality, recovery, and lean mass.
PT-141
Bremelanotide (Vyleesi)
A melanocortin receptor agonist and the first FDA-approved on-demand treatment for low sexual desire, acting on brain arousal pathways rather than vascular ones (unlike PDE5 inhibitors). Widely used off-label/in research for libido and arousal support in men.
SLU-PP-332
Synthetic ERRα/β/γ pan-agonist (exercise mimetic research chemical)
A first-in-class synthetic pan-agonist of the estrogen-related receptors (ERRα/β/γ) — orphan nuclear receptors that govern mitochondrial biogenesis and oxidative metabolism in skeletal muscle. Functions as a pharmacological 'exercise mimetic,' reproducing key transcriptional and endurance effects of aerobic training in mice without exercise.
DSIP
Delta Sleep-Inducing Peptide
A nonapeptide first isolated from rabbit brain blood during induced slow-wave sleep. Studied for effects on sleep architecture and HPA-axis/cortisol regulation, though the best-controlled human trial found only modest, inconsistent benefit for chronic insomnia.
IGF-1 LR3
Long R3 Insulin-like Growth Factor-1
An engineered IGF-1 analog with a Glu3→Arg3 substitution and a 13-amino-acid N-terminal extension that drastically reduces its binding to IGF-binding proteins, extending its active window and biological potency far beyond native IGF-1.
CJC-1295
Growth Hormone Releasing Hormone analog
A GHRH analog that stimulates growth hormone release. Often stacked with Ipamorelin for synergistic GH pulse amplification, improved body composition, and recovery.
GHRP-6
Growth Hormone Releasing Peptide-6
The original ghrelin-mimetic GH secretagogue — a hexapeptide that stimulates pulsatile GH release through the same receptor as endogenous ghrelin. Its strong appetite-stimulating effect is a hallmark side effect, useful during bulking phases but often unwanted otherwise.
HCG
Human Chorionic Gonadotropin (Novarel / Pregnyl)
An LH-receptor agonist that directly stimulates Leydig cells to keep testosterone production and testicular size intact — the most established and widely used TRT adjunct for preserving fertility and preventing testicular atrophy.
Kisspeptin
KISS1 Gene-Derived Neuropeptide (Metastin)
The master upstream regulator of the reproductive axis — kisspeptin neurons trigger pulsatile GnRH release from the hypothalamus. Investigated in clinical trials for its downstream effects on LH/FSH pulsatility and, more recently, for direct effects on sexual arousal and desire.
Pinealon
Glu-Asp-Arg (EDR) Tripeptide Bioregulator
A synthetic tripeptide (Glu-Asp-Arg) from Khavinson's short-peptide bioregulator research, designed as a brain-tissue-specific analog. Studied for neuroprotective, learning, and antioxidant effects in aged-animal models — a shorter cousin of Epitalon focused on cortical tissue rather than the pineal-retina axis.
Cagrilintide
Long-Acting Amylin Receptor Agonist
A long-acting amylin receptor agonist that suppresses appetite via a pathway distinct from GLP-1. Most notable paired with semaglutide as 'CagriSema,' which outperformed semaglutide monotherapy for weight loss in phase 3 trials.
FOX-04 DRI
FOXO4 D-Retro-Inverso senolytic peptide
A synthetic retro-inverso peptide, fused to a cell-penetrating D-arginine tag, that selectively disrupts the FOXO4–p53 protein interaction inside senescent cells — triggering p53 nuclear exclusion and apoptosis specifically in senescent cells while sparing healthy tissue in mouse models.
LL-37
Cathelicidin antimicrobial peptide
A human cathelicidin peptide with broad-spectrum antimicrobial, wound healing, and immune-modulating properties. Promotes angiogenesis and disrupts bacterial biofilms.
Selank
Tuftsin analog
An anxiolytic peptide that modulates GABA-A receptors and serotonin systems. Reduces anxiety without sedation or dependence — a cleaner alternative to benzodiazepines.
Thymosin Alpha-1
Zadaxin
A naturally occurring thymic peptide that activates T-lymphocytes, NK cells, and dendritic cells. Approved in 35+ countries for hepatitis and cancer immunotherapy support.
Tirzepatide
Mounjaro / Zepbound analog
A dual GLP-1 and GIP receptor agonist (twincretin) that outperforms semaglutide in head-to-head weight loss trials, reaching ~20–22% body weight reduction.
5-Amino-1MQ
5-Amino-1-Methylquinolinium (NNMT inhibitor)
A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), a metabolic enzyme upregulated in adipose tissue. By blocking NNMT, it raises intracellular NAD+ and SAM levels and suppresses lipogenesis — reversing diet-induced obesity in mouse models.
GHRP-2
Growth Hormone Releasing Peptide-2 (Pralmorelin)
A more potent ghrelin-receptor GH secretagogue than GHRP-6, with substantially less appetite stimulation. Used clinically in Japan as a diagnostic test for GH deficiency, giving it one of the better human dosing/PK datasets among the GHRPs.
Gonadorelin
Synthetic Gonadotropin-Releasing Hormone (GnRH)
The synthetic form of the hypothalamic hormone that drives the entire reproductive axis. In TRT contexts, low-dose pulsatile gonadorelin is used to keep the pituitary-testicular axis active and preserve testicular size/fertility — a more physiologic alternative to hCG.
Hexarelin
Hexarelin (Examorelin)
The most potent GH secretagogue in the GHRP family, with a distinct non-GHSR cardiac receptor (CD36) that mediates direct cardioprotective effects independent of GH release. Prone to rapid receptor desensitization with prolonged use.
Mazdutide
Dual GLP-1/Glucagon Receptor Agonist (IBI362)
A dual GLP-1 and glucagon receptor agonist developed in China (Innovent Biologics) that pairs appetite suppression with glucagon-driven energy expenditure, showing strong weight loss and metabolic benefits in Chinese trials as an alternative to tirzepatide-class twincretins.
Melanotan I
Afamelanotide (NDP-α-MSH) analog
A synthetic analog of alpha-MSH (identical in structure to afamelanotide) that selectively activates the MC1 receptor to stimulate eumelanin production. Produces a more even, UV-independent tan with a substantially cleaner side effect profile than the non-selective Melanotan II.
Melanotan II
Non-selective melanocortin receptor agonist (MT-II)
A cyclic non-selective melanocortin receptor agonist (MC1R/MC3R/MC4R) that produces pronounced skin tanning along with off-target libido and appetite-suppressing effects. The parent compound from which bremelanotide (PT-141) was later developed as a selective, FDA-approved sexual-dysfunction therapeutic.
MGF
Mechano Growth Factor (IGF-1 Ec/Eb splice variant peptide)
The synthetic C-terminal peptide of the Ec (human) / Eb (rodent) splice variant of the IGF-1 gene — the 'mechano' variant muscle transiently expresses after mechanical loading or injury to activate dormant satellite cells before the tissue shifts to systemic IGF-1Ea for the actual growth/repair phase.
Oxytocin
Endogenous Neurohypophyseal Nonapeptide
An endogenous neuropeptide hormone studied for its role in social bonding, trust, and anxiety modulation, alongside a separate, well-established physiological role in uterine contraction and lactation.
PEG-MGF
PEGylated Mechano Growth Factor
A PEGylated version of the synthetic C-terminal peptide of the MGF splice variant of IGF-1, designed to extend the very short active window of native MGF for sustained local muscle-repair signaling. Popular in the research-peptide market, but PEG-MGF itself has essentially no direct peer-reviewed literature — the evidence base is the native, non-PEGylated MGF splice variant.
Semaglutide
Ozempic / Wegovy analog
A GLP-1 receptor agonist that regulates appetite, blood sugar, and promotes significant fat loss. The most clinically validated peptide for metabolic health optimization.
Sermorelin
GRF 1-29 NH2
A synthetic GHRH analog that stimulates pulsatile GH secretion from the pituitary. The fully compoundable alternative to CJC-1295 — on the 503A bulks list.
SNAP-8
Acetyl Octapeptide-3
A topical octapeptide that competes with SNAP-25 in the SNARE complex, relaxing facial muscles to reduce expression lines. A non-injection alternative to Botox.
Thymalin
Thymus Peptide Bioregulator Complex
A polypeptide complex extracted from calf thymus, part of Khavinson's original bioregulator research line out of St. Petersburg. Studied for restoring T-cell function and immune competence in aging populations, typically paired with the pineal peptide Epithalamin in longevity trials.
VIP
Vasoactive Intestinal Peptide
An endogenous 28-amino-acid neuropeptide with wide-ranging roles in immune tolerance, gut-brain signaling, and mast cell biology. Best known outside academic immunology as the closing step in mold-illness/CIRS practitioner protocols, dosed intranasally.
Educational Only. Not medical advice. Personalized protocols are provided through licensed Stackhaus Health providers.