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Muscle & PerformanceBeginnerCompoundable

Sermorelin

GRF 1-29 NH2

Low Dose
100 mcg/night
Medium Dose
300 mcg/night
Route
SubQ nightly
Cycle Length
16–24 weeks

Mechanism of Action

Synthetic analog of endogenous GHRH. Binds pituitary GHRH receptors to stimulate pulsatile GH secretion naturally, preserving the body's feedback loop.

Key Benefits

  • Restored youthful GH pulse amplitude
  • Improved lean body mass and reduced fat mass
  • Better sleep quality
  • Improved skin elasticity and recovery
  • Works through the natural feedback loop

Dosing Protocol

Low / Starting Dose
100 mcg/night
Medium / Maintenance Dose
300 mcg/night
Administration Route
SubQ nightly
Half-Life
~10–20 minutes
Frequency
Daily before sleep
Cycle Length
16–24 weeks
Protocol Notes

Inject 30 min before sleep on an empty stomach. On the 503A bulks list.

Ideal Candidates

Adults with GH decline, anti-aging, body recomposition, sleep optimization.

Side Effects & Safety

Injection site redness, flushing, headache. Rare water retention. Very well-tolerated.

Regulatory Status

Compoundable

On the 503A bulks list. Core HRT product with regulatory clarity.

Frequently asked

What is Sermorelin?+

Sermorelin (GRF 1-29 NH2) is a peptide studied for natural gh stimulation and lean body mass. Synthetic analog of endogenous GHRH. Binds pituitary GHRH receptors to stimulate pulsatile GH secretion naturally, preserving the body's feedback loop.

What is the dosing protocol for Sermorelin?+

Literature commonly references 100 mcg/night (low) to 300 mcg/night (maintenance) via SubQ nightly, on a 16–24 weeks cycle. Educational reference only — a licensed Stackhaus Health provider sets any personalized protocol.

What is the regulatory status of Sermorelin?+

On the 503A bulks list. Core HRT product with regulatory clarity.

Where can I access Sermorelin?+

Research-grade Sermorelin is available through Stackhaus Research. For a personalized, provider-reviewed protocol, consult a licensed clinician through Stackhaus Health.

More in Muscle & Performance

Educational Only. This information is not medical advice. Consult a qualified healthcare professional before starting any peptide protocol. Individual results vary. Personalized protocols and clinical care are provided through licensed providers via Stackhaus Health.